Centre for Molecular Biology, Max Perutz Labs

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  • Department of Chromosome Biology
    • Univ.-Prof. Mag. Dr. Verena Jantsch-Plunger    

      Research Focus:
      Chromosomes are the biologically relevant form of organization of the genome in all known forms of life. Correct transmission of genetic and epigenetic information, genome stability and the production of germ cells during sexual reproduction are key topics in chromosome biology. These subtopics are medically relevant (cancer, ageing, development, fertility, gene therapy), but also have economic importance (breeding). In my group we increase our understanding how genomes are segregated into germ cells and how genome integrity is preserved during gametogenesis. In particular, we are interested in meiotic chromosome movements, nuclear envelope reorganisation during movements and recombination/ DNA repair. We use Caenorhabditis elegans as our model system and take advantage of a combination of genetic, biochemical and imaging approaches. The Jantsch lab is embedded in the vibrant campus of the Vienna Bio Center with excellent state-of-the-art facilities. Furthermore we are part of the Special Research Program “ Meiosis”, which comprises 9 groups conducting research on meiosis.   

      More information can be found at:
      www.maxperutzlabs.ac.at/research/research-groups/jantsch

     

     

  • Department of Microbiology, Immunobiology and Genetics
    • Assoz. Prof. Christa Bücker, PhD

      Research Focus
      We study how enhancers interact with their target gene in the complex regulatory landscapes of the cells to activate gene expression.

      More information can be found at
      https://www.maxperutzlabs.ac.at/research/research-groups/buecker

    • Assoz. Prof. Alexander Dammermann, Privatdoz. BA MA PhD

      Research Focus
      Cell biology; Centrioles, centrosomes and cilia; Cell division; Evolutionary diversity

      More information can be found at
      http://www.maxperutzlabs.ac.at/dammermann 

    • Univ.-Prof. Mag. Dr. Pavel Kovarik

      Research Focus:
      Our research aims at understanding of how immune homeostasis is maintained and how a robust but not exaggerated immune response is accomplished. Defense against infectious agents and damaging cues requires efficient activation of inflammatory response and timely re-establishment of immune homeostasis once the hostile microbial or sterile cues have been eliminated. Unproductive responses result in infectious disease whereas failures in homeostatic processes cause tissue damage and prevent healing. Thus, inflammatory response needs to be strong but quantitatively and timely restricted. Although many of the inflammation-promoting and –controlling processes are known, the basic question of how these processes are coordinated in the context of balanced tissue-protective immune responses remains poorly understood.
      We study the molecular wiring of robust yet controlled inflammation at the level of transcription, mRNA decay and signaling.

      More information can be found at:
      https://www.maxperutzlabs.ac.at/research/research-groups/kovarik
    • Univ.-Prof. Dr. Kristin Tessmar-Raible

      Research Focus:
      Bridging from ecology to molecular biology: Biological Timers set by sun and moon.

      More information can be found at:
      http://www.univie.ac.at/gem/ 
  • Structural and Computational Biology